Planarian Regeneration: Its End Is Its Beginning
نویسندگان
چکیده
منابع مشابه
Planarian Regeneration: Its End Is Its Beginning
In 1901, Thomas Hunt Morgan wrote: " The fact that the process of regener-ation is useful to the organism cannot be made to account for its existence in the organism " (Morgan, 1901). Although such words may strike us today as being counter to the general concepts of natural selection, Morgan reached this conclusion after an exhaustive study of regeneration in both plants and animals (Morgan, 1...
متن کاملPlanarian regeneration: its end is its beginning.
Why does regeneration take place in some animals but not others? Increased understanding of gene function is required to dissect the genetics, cell biology, and physiological aspects that make regeneration possible. An unlikely model animal, the planarian Schmidtea mediterranea, is proving valuable in this endeavor.
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متن کاملFundamentals of planarian regeneration.
The principles underlying regeneration in planarians have been explored for over 100 years through surgical manipulations and cellular observations. Planarian regeneration involves the generation of new tissue at the wound site via cell proliferation (blastema formation), and the remodeling of pre-existing tissues to restore symmetry and proportion (morphallaxis). Because blastemas do not repla...
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Neurodegenerative and cardiovascular diseases, as well as stroke, infection and injury, require therapies that aim to replace lost, damaged or inoperative tissues. Regenerative medicine is therefore a major focus of medical research. Whereas regeneration in humans is limited, several vertebrates, such as salamanders and fish, can regenerate amputated body parts with high efficiency (reviewed in...
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ژورنال
عنوان ژورنال: Cell
سال: 2006
ISSN: 0092-8674
DOI: 10.1016/j.cell.2006.01.012